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Acetaminophen overdose is a major cause of acute liver failure and is the most common identifiable cause of acute liver failure in children.1 Repeated supratherapeutic dosing, accidental overdose due to error and intentional ingestion can all result in acute liver failure and even death

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12.7 Allosteric regulation of phosphofructokinase-1 (PFK-1) by ATP

We utilized network pharmacology to systematically explore the mechanism of action of glutathione on heart failure and identified genes and pathways as potential therapeutic targets for heart failure