Accountability Accountability covered aspects such as access to coaching, group support, progress tracking tools, and reminders
Effect on Obesity and Diabetes Obesity, particularly central obesity, is a major contributor to metabolic syndrome, which includes insulin resistance, type 2 diabetes, dyslipidemia, and hypertension
Discontinuation rates due to gastrointestinal adverse effects ranged from 4% to 7% across clinical trials
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Pharmacokinetic analysis revealed that there was no discernible accumulation of SalB in the body as the maximum plasma concentration and area under the curve (AUC) rose proportionately with increasing doses (Bi et al., 2016)
Preventive Services Task Force recommends that clinicians screen for obesity in children and adolescents aged 6 years and older and offer or refer them to comprehensive, intensive behavioural interventions to promote improvements in weight status [50]
