More concretely, RhGLP-1 lowered blood glucose in a dose-dependent manner while decreased the blood levels of biomarkers S100 Calcium Binding Protein B (S100B), major basic protein (MBP), and neuron specific enolase (NSE) which reflect cerebral damage (90) when administration implemented 2 weeks before transient middle cerebral artery occlusion (tMCAO) in diabetic rats
On the other hand, it is essential to explore potential differences among drugs by comparing the central action characteristics of different GLP 1 receptor agonist (GLP 1RA) formulations
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These mechanisms operate through different biological pathways with minimal direct pharmacokinetic interaction
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