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A variety of tissue engineering methods have been applied to cancer research, not only to support repair but also to mimic the native TME for in vitro modelling, including using patient-derived cells to obtain more clinically relevant data (Unnikrishnan et al., 2021), drug screening and toxicity studies for radiotherapy and chemotherapy (Xu et al., 2014)

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Low GSH levels associate with metabolic syndrome, cardiovascular disease, chronic kidney disease, NAFLD/NASH, Parkinsons disease, Alzheimers disease, autoimmune conditions, HIV infection, and cancer

The elevation of ROS within tumor cells has been associated with several detrimental effects, including enhanced cell proliferation, facilitation of mutations and heightened genetic instability (86)

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GST helps to manage free radical damage in multiple contexts [8,9]