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Wilding et al

MounjaroTM (tirzepatide) injection, for subcutaneous use: US prescribing information (2022)

There are also GLP-1 medications produced by compounding pharmacies, which use tirzepatide, semaglutide, or another GLP-1 receptor agonist

Any switch should still involve fresh titration from a starting dose under provider supervision, since individual tolerance varies

Trials have initiated treatment at a lower dose, with scheduled increases every four weeks to allow for monitoring of tolerability and side effects

High glucose exposure impairs L-cell differentiation in intestinal organoids: molecular mechanisms and clinical implications