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Downstream effects include concentration-dependent suppression of lipogenesis (50-70% reduction), decreased adipocyte size, and increased basal energy expenditure without appetite suppression

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Patients often prioritize outcomes such as: Daily functioning Fatigue Ability to work and maintain social activities Treatment convenience Emotional well-being Overall quality of life The integration of patient perspectives is helping create a more holistic understanding of treatment value and aligns closely with broader healthcare trends toward patient-centered and value-based care