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This process involves extensive animal testing followed by multiple phases of human clinical trials to establish both safety and efficacy

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3.1 Inhibition of MMP expression Matrix metalloproteinases (MMPs), a family of proteolytic enzymes critically implicated in tumor metastasis, drive cancer progression by degrading extracellular matrix (ECM) components and thus facilitating invasive cell behavior, with elevated MMP expression strongly correlating with aggressive metastatic phenotypes (Yang et al., 2014b)