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Probiotic-derived EPS activate TLR2 on DCs, fostering a tolerogenic phenotype characterized by IL-10 secretion and reduced autoreactive B/T cell activation (108, 146)

The enhanced production and release of ROS by activated inflammatory cells, macrophages, neutrophils and endothelial cells [23], are the main source of exogenous ROS

The phosphorylation leads to reduced affinity of the kinase for phosphoinositides

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We focus on small-batch synthesis with exact amino-acid sequencing

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