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Patients are sometimes surprised that we do not immediately increase their dose when they feel hungry early on

The cardiovascular outcomes trials that enrolled tens of thousands of patients with type 2 diabetesincluding LEADER (liraglutide), SUSTAIN-6 (semaglutide), REWIND (dulaglutide), and EXSCEL (exenatide ER)found no significant increase in overall cancer incidence compared to placebo over follow-up periods ranging from approximately two to five years

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