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Also, chronic circadian misalignment leads to immune suppression and low-grade systemic inflammation, both of which contribute to impaired tumor immunosurveillance 146
While several senolytic and senomorphic therapies show promise in clearing senescent cells and impacting age-related conditions, many lack data on CNS penetrance and efficacy in AD relevant systems
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Moore T, Le A, Niemi AK, Kwan T, Cusmano-Ozog K, Enns GM, Cowan TM (2013) A new LC-MS/MS method for the clinical determination of reduced and oxidized glutathione from whole blood
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