She noted that weight-loss drug Wegovy, which contains the same active ingredient as Ozempic, semaglutide, includes a warning about suicidal thoughts on its label. Sydney Lupkin goes on to describe an NPR analysis of the FDAs adverse event reporting system (FAERS)
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At 12 months, the liraglutide group tended to increase body weight compared to the placebo (L:0.9 kg, P:7.7 kg, p = 0.067, Table 2, Fig
More importantly, tight blood glucose control is essential during pregnancy, and the effects of GLP-1 drugs on blood sugar regulation can vary, potentially increasing the risk of hypoglycemia
Coverage of GLP-1s for weight loss has become particularly controversial: a 2025 ICER report noted only 18% of large employers cover these drugs ( [26] ), and 3052% of obesity-drug prescriptions were denied by payers as not covered ( [27] )