Ozempic is widely available for type 2 diabetes, while Wegovy was more recently launched in the Canadian market specifically for weight management
Insurance won't help with the monthly cost, but HSA/FSA funds may be applicable - confirm with your account provider
Phase 3 TRIUMPH-1 NCT05929066, TRIUMPH-2 NCT05929079, TRIUMPH-3 NCT05882045, TRIUMPH-4 NCT05931367, TRIUMPH-Outcomes NCT06383390
The $400 -$800 monthly cost is not maintainable for long for most people
Nearly half of people who say they have been diagnosed with diabetes (45%) report currently using a GLP-1 medication, as do three in ten (29%) adults who say theyve been diagnosed with heart disease and about a quarter (23%) of those who report being diagnosed as overweight or obese in the past five years
To study the role of GLP-1R in microglial inflammation, BV-2 cells were preincubated with the selective GLP-1R agonist liraglutide (100 nM, Selleck, TX, USA) and the antagonist exendin(939) (200 nM, MCE, USA) for 24 h, followed by LPS (1 g/ml, SigmaAldrich, MO, USA) stimulation for 24 h