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Mature IGFs are generated by proteolytic processing of inactive precursor proteins, which contain N-terminal and C-terminal propeptide regions

Evaluation for cross-conservation with the human genome using the JanusMatrix algorithm, however, revealed extensive human genome epitope homology at the TCR-facing residues of this peptide (see below)

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Reassess after 12 weeks to evaluate progress

Am J Cardiol 1998;82:737-43