Wessel MJ, Zimerman M, Timmermann JE, Heise KF, Gerloff C, Hummel FC
Clinical Benefits: Supports red blood cell formation and helps prevent megaloblastic anaemia Essential for neurological function and nerve tissue health Plays a key role in DNA synthesis and cell metabolism Supports cognitive function, concentration, and mood regulation Assists in the conversion of homocysteine, supporting cardiovascular health Helps address fatigue and weakness associated with B12 deficiency For patients presenting with deficiency, a loading protocol is typically recommended: weekly injections for three weeks, followed by monthly injections for three months, then a maintenance injection every three months
A rigorous LC-MS pharmacokinetic study in rats would provide a definitive reference
If you haven't done it already, I think it's a good idea to track down the local B12 deficiency guidelines used by your ICB (Integrated Care Board) in England (Health Boards in Wales/Scotland)
The duration it takes B12 to work depends on whether you take it daily or weekly
Use nonmetallic or nonreactive dishes, utensils, and cookware