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Multiple gut commensals, particularly lactic acid bacteria such as Lactobacillus and Bifidobacterium genera, express glutamate decarboxylase (GAD) and convert luminal glutamate into GABA [200]

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The documented mechanisms are: VEGF stimulation in dermal fibroblasts that supports the microvascular network feeding the follicle, collagen and glycosaminoglycan synthesis at the follicular basement membrane, anti-inflammatory signaling that calms the chronic micro-inflammation associated with androgenetic alopecia, and direct follicular signaling that extends the anagen growth phase

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Chapter IV: Insulin release