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Ispoglou et al

Started on Aug 30, 2020

## Metabolic Effects Beyond Weight ### Blood Sugar Control - **Semaglutide:** A1C reductions of 1.0-1.5% (extensive diabetes data from SUSTAIN trials) - **Retatrutide:** A1C reductions of 1.5-2.0% in Phase 2 (glucagon may enhance hepatic glucose metabolism) ### Cardiovascular Health - **Semaglutide:** The SELECT trial (2023) proved a 20% reduction in major adverse cardiovascular events

This weekly schedule makes it easy to remember and reduces the need for daily dosing

Patients still have to make the right choices, including eating the right foods, he says

I mean, I mentioned that Johnson and Johnson decided to sell one of its brand products directly to consumers through the cost plus pharmacy model, which is the Mark Cubans model that sells cash based pharmaceuticals directly to the patient and theyve discounted that drug by about 60%