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Although NRF2 does not directly regulate serine synthesizing enzyme genes, ATF4, a key regulator of serine synthesis, was shown to be activated by NRF2

The most pronounced delay is observed with short-acting agents, while long-acting agents (including both oral and injectable) show attenuation of this effect over time due to tachyphylaxis [20,21,22]

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Matrix mechanical plasticity regulates cancer cell migration through confining microenvironments

falciparum cultures were incubated in incomplete RPMI for 4h in presence of 0, 1 or 10M BAY 43-9006