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potentially fatal disturbances of cardiac conduction (widening of QRS), arrhythmias & seizures due to Na channel block (cardiac & CNS) Pharmacokinetics: PO, metabolized in the liver (P450 - 2D6)

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Such intermolecular disulfide links formed by protein degradation accumulate mispaired disulfide bonds and scrambled disulfide bridges, which can alter protein conformation and subunit associations (6)

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