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in preclinical and in-vitro systems it has been studied as a GHRH-receptor agonist on anterior pituitary cells, where it has been observed to stimulate the synthesis and pulsatile release of endogenous growth hormone
Its effects on inflammation run deep, operating through thiol-disulfide exchange reactions that modulate major signaling cascades such as NF-kB and MAPK pathways
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HSP, heat shock protein
Biomed Pharmacother 102:855864
Lipids in health and disease
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