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Time course experiments were performed using a single ligand concentration to determine the peak response time point (3min) for the subsequent concentration response curves as previously described
Qi R, Zhang B, Qiu X, Liu X, Bao S, Wang J, Wang Q, Yang Y, Yang H, Liu Z
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For instance, cosmetic-derived NPs have been found to exert cytotoxic effects on human keratinocytes by initiating oxidative stress responses, inhibiting cell division, and accelerating the onset of cellular aging [35]
Clinical research has demonstrated that a reduction in CBF occurs during the initial phases of the disease, suggesting a connection to Syn pathology and the aberrant activation of pericytes [27, 235, 236]
