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In patients with HBV infection, smoking further increased the HCC risk by 1.4-fold, and even more dramatically, in individuals with HCV infection, the risk of HCC was increased 2.9-fold if there was a history of cigarette smoking [102]

Pereira CPM, Souza ACR, Vasconcelos AR, Prado PS (2021) Antioxidant and anti-inflammatory mechanisms of action of astaxanthin in cardiovascular diseases

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The version with DAC (Drug Affinity Complex) binds to albumin in the blood, extending its half-life to approximately 8 days and allowing once-weekly dosing