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Metabolic stress, calcium dysregulation and neuroinflammation mediated by glial cells like astrocytes and microglia further exacerbates RGC loss ( In many eye diseases, oxidative stress and mitochondrial dysfunction are key contributors to RGC degeneration

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doi: 10.1016/0005-2728(78)90138-X 58 SchtzendbelA.NikolovaP.RudolfC.PolleA

Animal studies also suggest that it may help protect against arrhythmias and decrease heart damage caused by vascular blockage or ischemia