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Patients with a history of medullary thyroid carcinoma, severe kidney disease, or retinopathy should avoid semaglutide entirely, regardless of dosing strategy

Insulin secretion is stimulated, glucagon and gastric acid secretion are inhibited, and GI transit and motility are decreased by incretin hormones, especially glucagon-like peptide-1 (GLP-1), which is released postprandially from L-cells lining the gut in response to food ingestion (12)

Its ideal for patients with sagging skin or muscle separation after weight loss

If you experience significant nausea, vomiting, or other side effects, your prescriber can pause dose increases, lower your dose, or adjust your injection schedule

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Follow with a toner, if desired, to balance the skin's pH