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1 GLP-1RAs can be distinguished, according to their half-life and time-action profile, as short-acting (exenatide and lixisenatide) or long-acting (exenatide once-weekly, liraglutide, albiglutide, dulaglutide and semaglutide)

These substances contribute to insulin resistance, dyslipidemia, and systemic inflammationkey drivers of type 2 diabetes, cardiovascular disease, and metabolic dysfunction-associated steatotic liver disease (MASLD, formerly known as NAFLD)

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