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Evidence from a Molecular Pharmaceutics study shows acetate counterions can become part of peptide aggregates, so the acid plays a real role in solution behavior, but at the diluted concentrations used in reconstitution it primarily serves to keep the peptide clear and in solution
According to a commenter, even if CMS moved to market-based weights, it would still need cost data for other purposes (outlier payments, new technology add-on payments, etc.) and thus, hospitals would shoulder additional reporting duties rather than any offsetting reduction
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For the time period studied, the authors suggest that at least one channel through which MA plans paid lower prices was by obtaining greater discounts on types of FFS Medicare admissions that were known to have very short lengths-of-stay
Practical considerations often influence route selection beyond theoretical optimization
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