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A provider-led approach typically includes baseline metabolic assessment (fasting glucose, lipid panel, liver/kidney function), review of family history and personal tolerability patterns, and sometimes biomarker testing to inform starting dose and medication choice

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Following its physiological action, 1,25(OH)D is further catabolized by CYP24A1 into final metabolites such as calcitroic acid and 1,25(OH)D26,23 lactone, which are subsequently excreted in bile or urine [96, 102].(Fig

That's true for vitamin A, iron, and calcium