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Bottom: volcano plot showing relative fold change (log 2 ) in whole cell metabolite abundance versus log 10 (P value) from ER-tag HEK293T cells treated with thapsigargin compared to untreated

Two contrasting dietary models warrant consideration: the western-style and the MeD diet

In a murine model of myocardial infarction, four weeks of coronary blockage resulted in mitochondrial ROS formation, mainly hydroxyl radicals ( OH), decrease in mitochondrial DNA

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