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Patients with a mean baseline HbA1c of 8.1% (range 6.5%-10.7%) were randomized to receive either SYMLIN or placebo, both administered before major meals as add-on to insulin therapy

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At diagnosis, 22 40.5% of patients with acromegaly exhibit elevated fasting glucose concentrations and/or impaired glucose tolerance and 12 34.9% diabetes mellitus (3742)