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The FDA prescribing information lists diarrhea as an adverse reaction occurring in 30% of patients treated with the 2.4 mg injection compared with 16% on placebo in the weight-reduction trials

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10.1016/j.brainresbull.2015.12.007 24 JiangZ.LiuD.LiT.GaiC.XinD.ZhaoY.et al (2025)

Cerebrolysin, as a complex mixture, has specific handling requirements that differ from single-peptide compounds

Furthermore, since all the weight loss does not occur at once, normalizing EE to body weight in a group with fluctuating body weight can be problematic

Viribay A et al