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Pharmacokinetics in rats and monkeys In dose-matched pharmacokinetic comparisons within each species, conducted using the study-specific formulations reported by the investigators (the two peptides used different formulation conditions, including different pH values), eloralintide showed higher exposure, a longer apparent half-life, and a flatter concentration-time profile than cagrilintide

[DOI] [PubMed] [Google Scholar] 135.Mnzo Y.J., Hazout A., Panteix G., Robert F., Rollet J., Cohen-Bacrie P., Chapuis F., Clment P., Benkhalifa M

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Solvent dependence of dimensions of unfolded protein chains