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However, an excess of pro-angiogenic factors such as VEGF can trigger the production of pro-inflammatory cytokines and neuroinflammation, potentially contributing to neurodegeneration (McConnell et al

reported significant reductions in cystatin C levelsa sensitive marker of renal functionfollowing senescent cell clearance in murine fibrosis models, indicating meaningful functional preservation alongside attenuated fibrosis (Mylonas et al., 2021)

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It is currently believed that the protein level of SLC25A39 is regulated by a dual mechanism involving the mitochondrial protease ATPase family gene 3-like 2 (AFG3L2) and iron sensing [22, 23]

Sorafenib is an FDA-approved drug for the treatment of patients with advanced HCC, and it has been confirmed to be a potential ferroptosis inducer

Medical treatment, prescribing, diagnosis, and individualized care require an established relationship with a licensed clinician