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Prominent physical observations documented across trial cohorts include: Gastrointestinal disturbances including transient nausea, acute vomiting, and altered bowel motility

Drinking water is essential for the body to function

Despite their effectiveness, GLP-1 therapies are not without limitations

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The treatment of type 2 diabetes requires positive modulation of GLP-1R to inhibit glucagon secretion and stimulate insulin secretion in a glucose-dependent manner 2

Marso SP, Daniels GH, Brown-Frandsen K, Kristensen P, Mann JFE, Nauck MA, Nissen SE, Pocock S, Poulter NR, Ravn LS, Steinberg WM, Stockner M, Zinman B, Bergenstal RM, Buse JB