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Serious concerns like pancreatic or thyroid cancer remain unconfirmed due to their rarity.[6] While the risk of hypoglycemia is generally low, it increases when combined with insulin or sulfonylureas.[2] Upper respiratory infections were reported in several trials, particularly with oral semaglutide, though the mechanism remains unclear

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objective evidence varies

You can read the abstract of this article at LY3298176, a novel dual GIP and GLP-1 receptor agonist for the treatment of type 2 diabetes mellitus: From discovery to clinical proof of concept A novel dual GIP and GLP-1 receptor agonist, LY3298176, was developed to determine whether the metabolic action of GIP adds to the established clinical benefits of selective GLP-1 receptor agonists in type 2 diabetes mellitus (T2DM)

Alcohol Can Increase Dehydration Risk Alcohol acts as a diuretic, which increases fluid loss through urination