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This strategy prevents competitive interference from endogenous ligands and antibodies by using the insulin receptor and integrin v as model targets, respectively, and can effectively overcome pseudotargets or target loss caused by shedding or mutating the extracellular domain of target receptors

This would allow for inferences, such as the removal of diseased samples from healthy ones and the extraction of biomarkers for diagnostic purposes

Henderson SJ, Konkar A, Hornigold DC et al (2016) Robust anti-obesity and metabolic effects of a dual GLP-1/glucagon receptor peptide agonist in rodents and non-human primates

Aesthetic refinements in second toe-to-thumb transfer surgery

Phase 3 enrollment is currently in progress

The best choice depends on your full medical picture