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A 2026 meta-analysis of 821 patients on obesity-dose GLP-1 drugs found semaglutide (Ozempic, Wegovy) users lost the most lean mass of the drugs studied, 5.44 kg on average

In addition, HDL and cholesterol efflux were reported to suppress megakaryocyte progenitor proliferation, platelet levels, and thrombocytosis (826)

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When FAO or glycolytic flux is increased, carnitine maintains the balance of intracellular metabolism by buffering excess acetyl-CoA to prevent its accumulation to harmful levels [8]

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