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Although a causal relationship cannot be established, this finding indicates that MTX resistance in vitro is associated with specific metabolic responses by the cells under drug action

Reduces cancer risk Some scientific evidence suggests an association between the levels of vitamin D in the body and the risk of some cancers, although it's inconclusive

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Back Zander, M, Madsbad, S, Madsen, JL, Holst, JJ (9 March 2002) 'Effect of 6-week course of glucagon-like peptide 1 on glycaemic control, insulin sensitivity, and beta-cell function in type 2 diabetes: a parallel-group study', The Lancet , 359/9309, 824-30

and (iv) loss of function mutations in PTEN , encoding the phosphatase PTEN which inhibits PI3K