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They are not comparable to any over-the-counter patch on the market

The above strategies may lower the circulating TMAO levels by targeting gut microbiota, inhibiting the activity of TMA/TMAO production and conversion-related enzymes, and intervening in downstream effects, thereby providing a theoretical basis for the clinical treatment of TMAO-related diseases

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These side effects are usually manageable with proper monitoring and follow-up care, and in some cases, adjusting the dosage under medical supervision