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This was a small study in which metformin and glucose were administered as a single dose, intraduodenally a very artificial scenario

Enhances learning capacity and memory consolidation

Sensory : Infraorbital (upper lip) and mental (lower lip) branches of the trigeminal nerve

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Indications for GLP-1 agonist therapy include contraindications or intolerance to metformin or poorly controlled diabetes in patients already taking metformin

Eligible patients (N=135) between the ages of 10-17 years had A1C levels between 7%-11% if they were being treated with diet and exercise alone or between 6.5%-11% if they were being treated with metformin (with or without insulin) and had a body mass index (BMI) greater than the 85th percentile