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El efecto dermatolgico ms relevante en la investigacin es el oscurecimiento generalizado de la piel y, de forma especfica, la intensificacin y el cambio de aspecto de lunares, nevos y eflides (pecas), lo que obliga a vigilar cualquier lesin pigmentada

J Clin Oncol 2007

This is the required route under the Medicines for Human Use (Clinical Trials) Regulations 2004 (as amended) and MHRA/HRA guidance on CTIMP safety reporting

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A pathologist assessed the Picrosirius red sections and provided a METAVIR score following a protocol blinded to genotype

Traditional oral forms may be broken down during digestion before significant amounts reach circulation