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34 Angarita et al 15 found that pretreatment with a clinically relevant (antidiabetic) dose of exenatide (5 g, 0.02 mL) did not alter the cocaine-related behaviors or subjective effects such as euphoria and wanting cocaine in people with cocaine use disorder compared to placebo (saline 0.02 mL)

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Adding 3 mL of bacteriostatic water to a 30 mg vial gives 10 mg/mL, where 5 mg equals 50 units on an insulin syringe

FIGURE 2 5.1 Anti-neuroinflammatory effects The principal mechanism by which semaglutide exerts its neuroprotective effects is through the suppression of neuroinflammation

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Bedding was replaced daily, and both drinking water and food were sterile and nutritionally balanced