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In AD, along with amyloid and tau phosphorylation, there is an associated increase in inflammation/glial activation, a decrease in synaptic function, an increase in astrocyte activation, and a state of insulin resistance

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Importantly, ferroptosis is caspase independent and occurs when the antioxidant defense system, primarily the system Xc-/GSH/GPX4 axis, is compromised

1550 of 11/10/2022 adopted by the Italian Ministry of University and Research, CUP D93C22000890001, Project title Research and innovation network on food and nutrition Sustainability, Safety and Security Working ON Foods (ONFoods)

To maximize the benefits of these drugs, pair them with lifestyle changes like a well-balanced diet and regular exercise

Single-cell studies in recurrent implantation failure report persistent proliferative stromal programmes and incomplete progression toward decidual states, including in mid-luteal biopsies [297, 299]