METAOD001: A Phase I (double-blind, placebo-controlled, dose escalation) safety study with doses (ranging from 25 to 400 g/kg AOD9604) administered intravenously to 15 healthy adult male volunteers presenting with a BMI between 24 and 30 kg/m 2
But you can get it from fortified plant milks, breakfast cereals, and other foods (check the labels to make sure B12 is included)
A 2025 meta-analysis of 16 studies involving 6,098 participants found no statistically significant difference between intramuscular, oral, and sublingual B12 supplementation routes (p=0.270)
Neither route is universally better the right option depends on your medical history, goals, and your providers recommendation
Therefore, if you suspect vitamin B12 shots could be a great therapy for your deficiency symptoms, you should speak to your doctor or a wellness specialist at Next|Health
PMC 3370288