The trial currently has almost 10,000 patients enrolled and is expected to assess a composite MACE endpoint consisting of cardiovascular (CV) death, non-fatal myocardial infarction, or non-fatal stroke in patients with T2D as is expected to readout in July 2024 (NCT03574597)
The NBER study also didnt account for the high likelihood of discontinuation due to side effects, another factor health plan providers weigh when choosing to cover GLP-1s for obesity
Results tend to appear faster and more dramatically than topical application
Studies suggest that it may help regulate energy balance and food intake through these melanocortin pathways, contributing to broader metabolic and weight regulation research models
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