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Introduction Type 2 diabetes mellitus (T2DM), a chronic degenerative disease where the pancreas cannot produce enough insulin and/or the insulin produced is inefficient, causing hyperglycemia, is a major health problem and one of the top 10 causes of mortality worldwide ( From a clinical point of view, T2DM patients are often accompanied by obesity, atherosclerotic disease, dyslipidemia, and hypertension ( At present, many drugs have been used to control blood glucose and Body Mass in T2DM patients, among which Wang et al

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Current approved peptides have generally demonstrated favorable safety profiles, with most adverse effects being manageable and reversible