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A central conundrum in immunosenescence research lies in navigating the dual risks of therapeutic interventions: suppressing age-associated inflammation (inflammaging) may inadvertently exacerbate infection susceptibility or compromise basal immune homeostasis, whereas overactivating inflammatory pathways to restore immune function risks precipitates autoimmune pathologies or acute inflammatory sequelae

These findings support the gut-muscle-nerve axis as a targetable pathway in fibromyalgia and position ozone-based therapies as promising interventions

Kennedy et al., 2014

03 Potential for lower doses Using these medications in combination might allow for lower doses of each, potentially reducing side effects while maintaining efficacy

MASH is a more severe form of the liver disease MASLD, or metabolic dysfunction-associated steatotic liver disease