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This happens because building or maintaining muscle mass while losing fat creates periods where total body weight stays relatively constant despite significant body composition improvements

It does so by stimulating insulin release and reducing glucagon, among other actions

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These studies on rats caused a huge stir within the scientific community

Best taken 30 minutes before a workout for maximum metabolic benefit

Data from the Phase 2 programme (NEJM, 2023) provide an initial picture of its tolerability, which broadly mirrors that of other incretin-based therapies, with some additional considerations related to its glucagon receptor activity