Positive factors like vitamin intake further modulate activity
Search for transcription factor biding sites at the DML Transcription factor binding sites (TFBS) at the DML were searched in the JASPAR CORE 2022 database ( an open-access and regularly updated resource featuring manually curated transcription factor (TF) binding profiles 24,25
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This indicated that there is no significant correlation between genotype and clinical phenotype, which is consistent with other studies
Zou Y, Kennedy KG, Grigorian A, Fiksenbaum L, Freeman N, Zai CC, et al
For example, a combinatorial pretreatment with an antioxidant, a p53 inhibitor, and a neurotrophin provided significant multifactorial protection against cisplatin-induced ototoxicity in vitro and in cochlear explants, addressing concurrent biological mechanisms of cell death (Febles et al., 2022)