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In some embodiments, the otic formulation or composition comprises between about 1% to about 20% by weight of the therapeutic agent, or pharmaceutically acceptable prodrug or salt thereof

Lactate drives epithelial-mesenchymal transition in diabetic kidney disease via the H3K14la/Klf5 pathway

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Ye P, Cheah IK, Halliwell B (2013) A high-fat and cholesterol diet causes fatty liver in guinea pigs

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