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Sources: Sonthalia et al., 2018 , Narrative review, 2025 Precautions before treatment Disclose your full medical history, medicines and supplements Get a personalised dose and route from a qualified doctor Avoid if pregnant or breastfeeding Flag any known allergies or sensitivities Self-medication or IV use without medical supervision can pose serious health risks

Further changes in BBB integrity have been noted with changes in expression and function of BBB transporters and receptors such as GLUT1, LRP, or Pgp [103,104,105,106,107,108,109,110,111]

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