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& Grigson, P
GLP-1 inhibits intestinal contractions through mechanisms that may involve the central nervous system via vagal pathways or direct action on central receptors [24], as well as the enteric nervous system by modulating neurotransmission through presynaptic receptors affecting nitric oxide release [25,26]
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Weight changes associated with GLP-1 treatment may necessitate adjustment of thyroid hormone replacement doses, as body weight influences levothyroxine requirements
At that point, you have the freedom to re-evaluate your timing based on appetite alignment and convenience rather than side effect avoidance
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